peg conjugated lipid alc 0159 Search Results


alc 0159  (MedChemExpress)
95
MedChemExpress alc 0159
Alc 0159, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/peg+conjugated+lipid+alc+0159/ALC-0159/pm40133260-314-11-14
Average 95 stars, based on 1 article reviews
alc 0159 - by Bioz Stars, 2026-09
95/100 stars
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alc-0159  (Kyfora Bio)
N/A
ALC-0159 (N,N-dimyristylamide of 2-hydroxyacetic acid) is a PEGylated lipid commonly utilized in the formulation of lipid nanoparticles (LNPs) for the delivery of mRNA and other therapeutic agents. PEGylated lipids enhance the stability, circulation time, and
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lipid nanoparticles alc-0159  (BioNTech)
90
BioNTech lipid nanoparticles alc-0159
Lipid Nanoparticles Alc 0159, supplied by BioNTech, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/peg+conjugated+lipid+alc+0159/alc+0159/pmc09008488-153-8-7
Average 90 stars, based on 1 article reviews
lipid nanoparticles alc-0159 - by Bioz Stars, 2026-09
90/100 stars
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n ditetradecylacetamide  (Croda International Plc)
94
Croda International Plc n ditetradecylacetamide
N Ditetradecylacetamide, supplied by Croda International Plc, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/peg+conjugated+lipid+alc+0159/ALC-0159/pmc12300687-78-29-79
Average 94 stars, based on 1 article reviews
n ditetradecylacetamide - by Bioz Stars, 2026-09
94/100 stars
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alc 0315  (Molecular Dynamics Inc)
86
Molecular Dynamics Inc alc 0315
Alc 0315, supplied by Molecular Dynamics Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/peg+conjugated+lipid+alc+0159/0315+alc/pm40629129-99-16-0
Average 86 stars, based on 1 article reviews
alc 0315 - by Bioz Stars, 2026-09
86/100 stars
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pegylated lipid alc-0159  (MedKoo Inc)
90
MedKoo Inc pegylated lipid alc-0159
Pegylated Lipid Alc 0159, supplied by MedKoo Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/peg+conjugated+lipid+alc+0159/methoxypolyethyleneglycoloxy+2000++n+n+ditetradecylacetamide++alc+0159/pmc12039171-71-11-15
Average 90 stars, based on 1 article reviews
pegylated lipid alc-0159 - by Bioz Stars, 2026-09
90/100 stars
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alc-0159  (MedKoo Inc)
90
MedKoo Inc alc-0159
Systemic immunogenicity and safety evaluation. a, Heatmap showing log fold change compared to PBS-treated mice for 32 different cytokines and chemokines. b, SM-102 based LNPs, comparison between DMG-pSar 25 and DMG-PEG 2000 LNPs. c, ALC-0315 based LNPs, comparison between DMG-pSar 25 and <t>ALC-0159</t> LNPs. d, Comparison of relative cytokine and chemokine expression of DMG-pSar 25 formulated with SM-102 or ALC-0315. e, ALT and AST quantitation. Data in b to e are presented as mean ± s.d. and statistical significance was analyzed by two-tailed Student's t -test. * P < 0.05, ** P < 0.01, *** P < 0.001, ns, no significance.
Alc 0159, supplied by MedKoo Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/peg+conjugated+lipid+alc+0159/alc+0315/pmc10957522-36-3-9
Average 90 stars, based on 1 article reviews
alc-0159 - by Bioz Stars, 2026-09
90/100 stars
  Buy from Supplier
lnps alc-0315 alc-0159 dspc cholesterol  (BioNTech)
90
BioNTech lnps alc-0315 alc-0159 dspc cholesterol
Representative completed and ongoing clinical studies (immunotherapy)
Lnps Alc 0315 Alc 0159 Dspc Cholesterol, supplied by BioNTech, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/peg+conjugated+lipid+alc+0159/alc+0315/pmc11564800-1-11-52
Average 90 stars, based on 1 article reviews
lnps alc-0315 alc-0159 dspc cholesterol - by Bioz Stars, 2026-09
90/100 stars
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plasmolipin pllp nm 015993 human 3 utr clone  (OriGene)
N/A
3 UTR clone of plasma membrane proteolipid plasmolipin PLLP for miRNA target validation
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c14 dihydroceramide  (Aladdin Scientific Corporation)
N/A
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plasmolipin pllp nm 015993 human tagged orf clone  (OriGene)
N/A
PLLP Myc DDK tagged Human plasmolipin PLLP
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Image Search Results


Systemic immunogenicity and safety evaluation. a, Heatmap showing log fold change compared to PBS-treated mice for 32 different cytokines and chemokines. b, SM-102 based LNPs, comparison between DMG-pSar 25 and DMG-PEG 2000 LNPs. c, ALC-0315 based LNPs, comparison between DMG-pSar 25 and ALC-0159 LNPs. d, Comparison of relative cytokine and chemokine expression of DMG-pSar 25 formulated with SM-102 or ALC-0315. e, ALT and AST quantitation. Data in b to e are presented as mean ± s.d. and statistical significance was analyzed by two-tailed Student's t -test. * P < 0.05, ** P < 0.01, *** P < 0.001, ns, no significance.

Journal: Bioactive Materials

Article Title: Engineering LNPs with polysarcosine lipids for mRNA delivery

doi: 10.1016/j.bioactmat.2024.03.017

Figure Lengend Snippet: Systemic immunogenicity and safety evaluation. a, Heatmap showing log fold change compared to PBS-treated mice for 32 different cytokines and chemokines. b, SM-102 based LNPs, comparison between DMG-pSar 25 and DMG-PEG 2000 LNPs. c, ALC-0315 based LNPs, comparison between DMG-pSar 25 and ALC-0159 LNPs. d, Comparison of relative cytokine and chemokine expression of DMG-pSar 25 formulated with SM-102 or ALC-0315. e, ALT and AST quantitation. Data in b to e are presented as mean ± s.d. and statistical significance was analyzed by two-tailed Student's t -test. * P < 0.05, ** P < 0.01, *** P < 0.001, ns, no significance.

Article Snippet: SM-102, ALC-0315, and ALC-0159 PEG lipids were purchased from MedKoo Biosciences.

Techniques: Comparison, Expressing, Quantitation Assay, Two Tailed Test

Representative completed and ongoing clinical studies (immunotherapy)

Journal: Signal Transduction and Targeted Therapy

Article Title: Progress and prospects of mRNA-based drugs in pre-clinical and clinical applications

doi: 10.1038/s41392-024-02002-z

Figure Lengend Snippet: Representative completed and ongoing clinical studies (immunotherapy)

Article Snippet: , , BNT162b2 , COVID-19 , SARS-CoV-2 full-length spike protein , LNPs (ALC-0315, ALC-0159, DSPC, cholesterol) , Intramuscular injection , 2020-04-29 , Phase II/III , Completed , Good immune efficacy against COVID-19 with a sustained safety profile and acceptable adverse events, but the immune efficacy declines after 6 months , NCT04368728 , BioNTech SE , .

Techniques: Virus, Injection, Membrane, Immunopeptidomics, Adjuvant, Activity Assay, Plasmid Preparation, Saline, Electroporation, Transfection, Inhibition

Representative preclinical studies (non-immunotherapy)

Journal: Signal Transduction and Targeted Therapy

Article Title: Progress and prospects of mRNA-based drugs in pre-clinical and clinical applications

doi: 10.1038/s41392-024-02002-z

Figure Lengend Snippet: Representative preclinical studies (non-immunotherapy)

Article Snippet: , , BNT162b2 , COVID-19 , SARS-CoV-2 full-length spike protein , LNPs (ALC-0315, ALC-0159, DSPC, cholesterol) , Intramuscular injection , 2020-04-29 , Phase II/III , Completed , Good immune efficacy against COVID-19 with a sustained safety profile and acceptable adverse events, but the immune efficacy declines after 6 months , NCT04368728 , BioNTech SE , .

Techniques: Coagulation, Injection, Polymer, Blocking Assay